Product labeling for PO topotecan endorses avoiding concomitant usage of P-gp inhibitors; the interaction with IV topotecan could possibly be significantly less critical but remains likely of clinical significance
aspirin, cilostazol. Either increases toxicity of the other by pharmacodynamic synergism. Use Caution/Keep track of. The need for simultaneous use of small-dose aspirin and anticoagulant or antiplatelet agents are typical for clients with heart problems; watch carefully.
NSAIDs may perhaps diminish the antihypertensive impact of ACE inhibitors. The system of such interactions is probably going linked to the ability of NSAIDs to lessen the synthesis of vasodilating renal prostaglandins.
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AGGRENOX is contraindicated in people with known hypersensitivity to any with the product or service factors.
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Ingestion of drug inside forty eight several hours ahead of pressure screening with intravenous dipyridamole or other adenosinergic agents may well enhance danger for cardiovascular Negative effects of and may impair sensitivity of take a look at
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apalutamide will minimize the level or result of dipyridamole by expanding elimination. Use Warning/Monitor. Apalutamide weakly induces BCRP agenolx login and will lessen systemic publicity of drugs which can be BCRP substrates.
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acalabrutinib boosts outcomes of dipyridamole by anticoagulation. Modify Therapy/Observe Intently. Coadministration of acalabrutinib with antiplatelets or anticoagulants might additional enhance hazard of hemorrhage.
aspirin, alteplase. Both raises toxicity of the other by anticoagulation. Use Warning/Keep an eye on. The need for simultaneous usage of very low-dose aspirin and anticoagulant or antiplatelet agents are typical for people with heart problems; check intently.
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